Essential Ion Channel Methods


Author: P. Michael Conn
Publisher: Academic Press
ISBN: 9780123822376
Category: Science
Page: 632
View: 5748
DOWNLOAD NOW »
The rapid growth of interest and research activity in ion channels is indicative of their fundamental importance in the maintenance of the living state. This volume was prepared with a view toward providing a sampling of the range of molecular and physical methods that are significant for the study of ion channels. As part of the Reliable Lab Solutions series, Essential Ion Channel Methods brings together chapters from volumes 293 and 294 of Methods in Enzymology. The chapters have been selected by the editor and updated, when possible, by their original authors to include new research and references. The result is a set of chapters which make use of graphics, comparisons to other methods, and provide tricks and approaches that make it possible to adapt methods to other systems. Methods are presented in a fashion that allows their replication by individuals new to the field, yet providing valuable information for seasoned investigators. Highlights top downloaded and cited chapters, authored by pioneers in the field and enhanced with graphics and easy to follow methods Loaded with detailed protocols developed and used by leaders in the field Refines, organizes and updates popular methods from one of our top selling series, Methods in Enzymology

Essential Bioimaging Methods


Author: P. Michael Conn
Publisher: Academic Press
ISBN: 9780080963426
Category: Medical
Page: 450
View: 6809
DOWNLOAD NOW »
Need a tested, reliable method that works? Put Essential Bioimaging Methods to work for you. Editor Michael Conn has hand-picked the most robust methods from his previously-published volumes in the Methods in Enzymology series. Many of these methods have been briefly updated by the authors that created them and use them in their research, and this book further refines and organizes existing content and focuses on methods that work, including MRI, fMRI, PET, Microscopic optical imaging and other. Part of the Reliable Lab Solution series, this volume provides clear advice and explicit protocols, providing updates to classic, tried-and-true methods and an essential addition to the bookshelf or workbench of any researcher in the field. * Highlights usefulness of techniques in basic research detailing MRI imaging of small animals, fMRI of Macaque monkeys, and baboon model of reperfused stroke * Built from volumes in the flagship brand, Methods in Enzymology * Provides tricks, tips and different approaches

Handbook of Ion Channels


Author: Jie Zheng,Matthew C. Trudeau
Publisher: CRC Press
ISBN: 1466551429
Category: Medical
Page: 691
View: 3104
DOWNLOAD NOW »
The New Benchmark for Understanding the Latest Developments of Ion Channels Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of cells. In nonexcitable tissues, they also help regulate basic salt balance critical for homeostasis. All of these features make ion channels important targets for pharmaceuticals. Handbook of Ion Channels illustrates the fundamental importance of these membrane proteins to human health and disease. Renowned researchers from around the world introduce the technical aspects of ion channel research, provide a modern guide to the properties of major ion channels, and present powerful methods for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook first describes the basic concepts of permeation and gating mechanisms, balancing classic theories and the latest developments. The second part covers the principles and practical issues of both traditional and new ion channel techniques and their applications to channel research. The third part organizes the material to follow the superfamilies of ion channels. This part focuses on the classification, properties, gating mechanisms, function, and pharmacology of established and novel channel types. The fourth part addresses ion channel regulation as well as trafficking and distribution. The final part examines several ion channel-related diseases, discussing genetics, mechanisms, and pharmaceutical advances.

Laboratory and Field Testing of Unsaturated Soils


Author: Alessandro Tarantino,Enrique Romero,Yu-Jin Cui
Publisher: Springer Science & Business Media
ISBN: 1402088191
Category: Science
Page: 214
View: 6787
DOWNLOAD NOW »
This volume details recent global advances in laboratory and field testing of unsaturated soils. Coverage includes mechanical, hydraulic, and geo-environmental testing and applications of unsaturated soil monitoring to engineering behavior of geo-structures.

Schmidek and Sweet: Operative Neurosurgical Techniques E-Book

Indications, Methods and Results (Expert Consult - Online and Print)
Author: Alfredo Quinones-Hinojosa
Publisher: Elsevier Health Sciences
ISBN: 1455723282
Category: Medical
Page: 2592
View: 2332
DOWNLOAD NOW »
Wherever, whenever, or however you need it, unmatched procedural guidance is at your fingertips with the new edition of Schmidek & Sweet: Operative Neurosurgical Techniques! Completely revised under the auspices of new editor-chief Dr. Alfredo Quiñones-Hinojosa, this comprehensive medical reference examines indications, operative techniques, complications, and results for nearly every neurosurgical procedure. Full-color illustrations, 21 new chapters, internationally-acclaimed contributors, surgical videos, and online access make it a "must have" for today's practitioner. Hone your skills for Master virtually every routine and specialized procedure for brain, spinal, and peripheral nerve problems in adult patients. Review clinical information on image-guided technologies and infections. Easily understand and apply techniques with guidance from more than 1,600 full-color illustrations. Rely on the knowledge and experience of new editor-in-chief Dr. Alfredo Quiñones-Hinojosa and leading international authorities, who offer multiple perspectives on neurosurgical challenges, from tried-and-true methods to the most current techniques. See exactly how to proceed with online surgical videos that guide you through each technique and procedure to ensure the best possible outcomes and results. Apply the latest techniques and knowledge in deep brain stimulation for epilepsy, movement disorders, dystonia, and psychiatric disorders; surgical management of blast injuries; invasive electrophysiology in functional neurosurgery; and interventional management of cerebral aneurysms and arterio-venous malformations. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more at www.expertconsult.com.

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book


Author: Richard A. McPherson,Matthew R. Pincus
Publisher: Elsevier Health Sciences
ISBN: 1455726842
Category: Medical
Page: 1568
View: 8313
DOWNLOAD NOW »
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Physiology of Excitable Membranes

Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980
Author: J. Salánki,H. Meves,N. Chalazonitis
Publisher: Elsevier
ISBN: 1483146928
Category: Science
Page: 370
View: 3994
DOWNLOAD NOW »
Physiology of Excitable Membranes contains plenary lecture and most of the papers presented at five symposia of the Section ""General Cell Physiology"" at the 28th International Congress of Physiological Sciences. Organized into 44 chapters, this book begins with a discussion on the ionic mechanisms of excitability of nerve cells. Subsequent chapters focus on charge movement in nerve membrane; calcium electrogenesis; optical changes during electrogenesis; synaptic transmission and modulation; and transmission in autonomic ganglia.

Steam, Water, and Hydrothermal Systems

Physics and Chemistry Meeting the Needs of Industry : Proceedings of the 13th International Conference on the Properties of Water and Steam
Author: Peter R. Tremaine,International Association for the Properties of Water and Steam
Publisher: NRC Research Press
ISBN: 0660177781
Category: Feed-water
Page: 954
View: 1499
DOWNLOAD NOW »
This work includes 140 papers on pure and applied research of physics and chemistry of hydrothermal systems. It includes papers on metastable states, nucleation, super-cooled water and high temperature aqueous solutions.

American Biotechnology Laboratory


Author: N.A
Publisher: N.A
ISBN: N.A
Category: Biology
Page: N.A
View: 5863
DOWNLOAD NOW »


Forensic Toxicology

Principles and Concepts
Author: Nicholas T Lappas,Courtney M Lappas
Publisher: Academic Press
ISBN: 0128004649
Category: Law
Page: 376
View: 1402
DOWNLOAD NOW »
Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies. Significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases The book's companion website, http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780127999678 features exclusive web-based content

Scientific Essentials of Reproductive Medicine


Author: Stephen G. Hillier
Publisher: Saunders
ISBN: N.A
Category: Fetus
Page: 599
View: 7655
DOWNLOAD NOW »
Addressing the scientific basis of obstetrics and gynaecology in the 1990s, this textbook focuses on the fundamentals of reproductive medicine from the perspective of molecular and cellular biology. It is aimed primarily at trainees, in particular MROG Part 1 candidates.

Ion channels of vascular smooth muscle cells and endothelial cells

proceedings of the International Society for Heart Research (ISHR) held in Cincinnati, Ohio, May 28 through June 2, 1991
Author: International Society for Heart Research. Meeting,Hiroshi Kuriyama
Publisher: Elsevier Science Ltd
ISBN: N.A
Category: Science
Page: 374
View: 596
DOWNLOAD NOW »


Tennessee Farm and Home Science

Progress Report
Author: N.A
Publisher: N.A
ISBN: N.A
Category: Agriculture
Page: N.A
View: 3722
DOWNLOAD NOW »


Performance Criteria for Concrete Durability


Author: H. Hilsdorf,J. Kropp
Publisher: CRC Press
ISBN: 0203626672
Category: Architecture
Page: 226
View: 3075
DOWNLOAD NOW »
This is a state-of-the-art report prepared by RILEM Technical Committee 116-PCD and is an authoritative, international review of the subject and is an essential reference source for engineers and technologists. Performance Criteria for Concrete Durability explains key aspects of concrete durability, and the relationships between transport mechanisms and concrete durability characteristics. It reviews test methods for measuring permeability in the laboratory and on site, and discusses the many factors which influence the durability of concrete to carbonation, chlorides, abrasion etc.

Dissertation Abstracts International

The sciences and engineering
Author: N.A
Publisher: N.A
ISBN: N.A
Category: Science
Page: N.A
View: 6716
DOWNLOAD NOW »


Membranen tierischer Zellen


Author: Antony Peter Murray Lockwood
Publisher: Springer-Verlag
ISBN: 332291223X
Category: Technology & Engineering
Page: 125
View: 4792
DOWNLOAD NOW »


Biennial Report


Author: University of California (System). Sea Grant College Program
Publisher: N.A
ISBN: N.A
Category: Marine resources
Page: N.A
View: 2734
DOWNLOAD NOW »


University of California Sea Grant College Program Annual Report


Author: University of California (System). Sea Grant College Program
Publisher: N.A
ISBN: N.A
Category: Oceanography
Page: N.A
View: 2321
DOWNLOAD NOW »


Geotechnical abstracts


Author: N.A
Publisher: N.A
ISBN: N.A
Category:
Page: N.A
View: 5228
DOWNLOAD NOW »