Advances in Comparative Immunology

This is the first revised textbook to offer a comprehensive review of recent and exciting advances in comparative immunology. The book presents an evolutionary approach to cellular and humoral immunity and reveals the immune system as ...

Author: Edwin L. Cooper

Publisher: Springer

ISBN: 9783319767680

Category: Medical

Page: 1048

View: 448

Download →

Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.
Posted in:

Advances in Comparative Immunology

There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology.

Author: Edwin Lowell Cooper

Publisher:

ISBN: 3319767690

Category: SCIENCE

Page:

View: 801

Download →

Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.
Posted in:

Invertebrate Pathology

Developmental and Comparative Immunology 55: 90–101 Smith, L.C., Arizza, V., Barela, M.A. et al. 2018. Echinodermata: The complex immune system of echinoderms. In Advances in Comparative Immunology. E.L. Cooper (ed.) pp. 409–509.

Author: Andrew F. Rowley

Publisher: Oxford University Press

ISBN: 9780198853756

Category: Medical

Page: 624

View: 469

Download →

This book assembles an international team of the leading specialists in the field to review the main diseases and pathologic manifestations of all the major invertebrate groups, whilst describing their emergence in contexts such as climate change and global food security.
Posted in:

Parasitology

(2018) Advances in Comparative Immunology. Springer. ISBN 978-3-31976767-3 ISBN 978-3-319-76768-0 (eBook) doi:10.1007/978-3-319-76768-0. Lemaitre B & Hoffmann J (2007) The host defense of Drosophila melanogaster.

Author: Eric S. Loker

Publisher: CRC Press

ISBN: 9781000544640

Category: Nature

Page: 652

View: 441

Download →

Produced amidst the still rippling effects of a pandemic and as the world experiences the increasing burden of global warming and a rapidly changing biosphere, the second edition of Parasitology: A Conceptual Approach offers a timely overview of the eukaryotic parasites affecting human health and the health of domestic and wild animals and plants. The book offers a broadly encompassing, integrative view of the phenomenon of parasitism and of the remarkable diversity of the world’s parasites. This second edition has been thoroughly updated on all aspects of parasitism, including expanded sections on parasite biodiversity, parasite genomes, the interface between parasitology and disease ecology, and applications of new techniques like CRISPR and gene drives for parasite control. Key selling features: Emphasis on a distinctive integrative and conceptual approach rather than the taxon-by-taxon approach used in most parasitology books A concise, handy Rogues Gallery section that summarizes the basic biology for the most important eukaryotic parasites of humans and domestic animals, one a reader is repeatedly directed to throughout the chapters Outstanding full-color illustrations and photographs to reinforce key points The use of text boxes to set apart important topics or ideas that deserve special emphasis Provision of end-of-chapter summaries, questions to test understanding and key references for those wishing to seek further information Reference to particular URLs to highlight recent developments that often pose new and distinctive problems awaiting solution Parasitology: A Conceptual Approach is designed for an upper-level undergraduate audience, but its readability and careful explanation of underlying scientific concepts and terminology makes it appropriate for anyone seeking a broader understanding of the impact of infectious organisms on our well-being and the changes underway in the modern world.
Posted in:

Aspects of Developmental and Comparative Immunology

Proceedings of the 1st Congress of Developmental and Comparative Immunology, 27 July - 1 August 1980, Aberdeen J. B. Solomon. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY I Book HADDEN Advances in Immunopharmacology Journals DEVELOPMENTAL ...

Author: J. B. Solomon

Publisher: Elsevier

ISBN: 9781483189710

Category: Science

Page: 590

View: 268

Download →

Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.
Posted in:

Invertebrate Immune Responses

Chapter 1, in this volume offers the bridge to Volume 23 and its final Chapter 7. This Volume 24 contains contributions pertaining to cell activities and the environment.

Author: E.L. Cooper

Publisher: Springer

ISBN: 354059468X

Category: Medical

Page: 280

View: 884

Download →

E. L. Cooper In Volume 23 we considered, in seven chapters, the basic armamentarium of the invertebrate immune system and its cells, as well as an analysis of antigens, setting the stage for the initiation of an immune response. We studied cell products, natural or induced, as revealed by nonspecific and specific responses following antigenic challenge such as the pro phenol oxidase system, the lytic responses, the Ig superfamily, and the place this family offers invertebrates and insect hemolymph proteins as candidates for membership. At this point, these various topics seemed to converge, almost to overlap, in some instances, presenting a challenge as to how to move from one subject to another. Chapter 1, in this volume offers the bridge to Volume 23 and its final Chapter 7. This Volume 24 contains contributions pertaining to cell activities and the environment. Chapters 1-4 refer specifically to interactions between cells and the integration of cell activities. The focus is on a functional immune system, with antigenic challenge as a subtopic. In Chapters 5-7, the environment is considered from several points of view and the main subtopic here is the result of the consequences of connections and missed signals. The internal and external environments are treated, revealing what may happen when normal immune responses are interfered with. All this is integrated by the consideration of the three great regulatory systems, the ever-present network that somehow acts as the monitor or control for all incoming and outgoing signals.
Posted in:

Evolutionary Parasitology

The Integrated Study of Infections, Immunology, Ecology, and Genetics Paul Schmid-Hempel. Group Some characteristics Mechanisms ... 1 See glossary for immunological acronyms . ... Advances in comparative immunology . Springer .

Author: Paul Schmid-Hempel

Publisher: Oxford University Press

ISBN: 9780198832140

Category: Medical

Page: 576

View: 108

Download →

Concepts from evolution, ecology, parasitology, and immunology have informed a new synthesis of host-parasite interactions. The book builds on these established approaches whilst including some of the most successful interdisciplinary areas of modern biology - evolutionary epidemiology and ecological immunology.
Posted in:

Pharmaceutical Biotechnology

This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology.

Author: Carlos A. Guzmán

Publisher: Springer

ISBN: 1441911316

Category: Medical

Page: 276

View: 190

Download →

Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.
Posted in:

Pharmaceutical Biotechnology

This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology.

Author: Carlos A. Guzmán

Publisher: Springer Science & Business Media

ISBN: 9781441911322

Category: Medical

Page: 276

View: 853

Download →

Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.
Posted in:

Index of NLM Serial Titles

... P14970000 PROBLEME DE PATHOLOGIE COMPARATA WI PR554N P25680000 COMPARATIVE ADVANCES IN COMPARATIVE PHYSIOLOGY AND ... ( 0010-4035 ) W1 C0434 033700000 COMPARATIVE GROUP STUDIES ( 0010-4108 ) W1 C0435H C33720000 COMPARATIVE IMMUNOLOGY ...

Author: National Library of Medicine (U.S.)

Publisher:

ISBN: UOM:39015074114672

Category: Medicine

Page:

View: 470

Download →

A keyword listing of serial titles currently received by the National Library of Medicine.
Posted in: