Clinical Management of Gastrointestinal Cancer

The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients.

Author: Jerome J. DeCosse

Publisher: Springer

ISBN: 1461328349

Category: Medical

Page: 396

View: 319

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Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need . It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal sub scription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourin ary cancer , pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basis biology, and more .
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New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors

This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors.

Author: Ernst D. Kreuser

Publisher: Springer Science & Business Media

ISBN: 9783642800351

Category: Medical

Page: 439

View: 999

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This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therapy. The second part of the volume offers new diagnostic tools, such as receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the multiple drug resistance gene, predicting response to therapy and prognosis in gastrointestinal tumors. The third part gives an update of successful approaches in primary and secondary prevention of colorectal carcinoma. Nutritional factors and pharmacologic agents can clearly decrease the risk, and fecal occult blood tests and endoscopy can reduce the mortality in colorectal carcinoma. Laparoscopic staging with subsequent biopsy of suspicious lymph nodes provides essential information in esophageal and gastric cancer. In locally advanced gastric cancer, preoperative chemotherapy provides sufficient evidence to investigate this approach as compared to primary surgery. Standards have recently been established in the adjuvant treatment of patients with gastrointestinal carcinoma, and promising new drugs, including monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, as well as taxoids, are currently being tested in phase I, II, and III trials of gastrointestinal tumors.
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Colorectal Cancer

Colorectal Cancer: Diagnosis and Clinical Management provides colorectal surgeons, gastroenterologists and oncologists with an authoritative, practical guide to best practice in the diagnosis and clinical management of colorectal cancer.

Author: John H. Scholefield

Publisher: John Wiley & Sons

ISBN: 9781118337899

Category: Medical

Page: 320

View: 153

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Colorectal Cancer: Diagnosis and Clinical Managementprovides colorectal surgeons, gastroenterologists and oncologistswith an authoritative, practical guide to best practice in thediagnosis and clinical management of colorectal cancer. Covering all forms of treatment including surgery, chemotherapyand radiotherapy, it examines the various new and emergingtherapies, new strategies for screening and prevention, as well asthe latest guidance on the most challenging and controversialaspects of managing colorectal cancer. The authors present important information on: Controversies in adjuvant chemotherapy Long versus short course radiotherapy Minimally invasive surgery and robotics Radical colonic resection Each chapter contains key points, tips and tricks and clinicalcase studies to aid rapid browsing and knowledge of the basicprinciples, while self-assessment questions allow readers to testtheir clinical knowledge. With leading international surgeons, gastroenterologists andoncologists combining to offer their considerable wealth ofexpertise and knowledge, Colorectal Cancer is awell-balanced, indispensable resource for all those involved incolorectal cancer management.
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Clinical Management of Gastrointestinal Cancer

Gunderson and colleagues from the Mayo Clinic outline the additive effects that radiation therapy may have in the management of rectal cancer. They discuss the preoperative, postoperative and sandwich techniques.

Author: Jerome J. DeCosse

Publisher: Springer Science & Business Media

ISBN: 9781461328339

Category: Medical

Page: 396

View: 612

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Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need . It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal sub scription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourin ary cancer , pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basis biology, and more .
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Gastric Cardiac Cancer

This book is designed to present readers with comprehensive, high-quality research results on almost all aspects of this carcinoma in clinical management, from correct determination of the esophagogastric junction, issues on cardiac mucosa, ...

Author: Qin Huang

Publisher: Springer

ISBN: 9783319791142

Category: Medical

Page: 328

View: 133

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This book is designed to present readers with comprehensive, high-quality research results on almost all aspects of this carcinoma in clinical management, from correct determination of the esophagogastric junction, issues on cardiac mucosa, epidemiology, and natural history, to clinical, endoscopic, and histopathologic features and diagnostic pitfalls of this carcinoma at both early and advanced stages. Once diagnosed and correctly staged, clinical management of this carcinoma at the early stage is addressed primarily with endoscopic therapy employing the latest endoscopic technology such as endoscopic submucosal dissection, in which detailed technical topics of the endoscopic therapy are written by experts in the field with sections from pre-resection staging and patient preparation to post-resection complications and management. Subsequently, clinical management of gastric cardiac carcinoma at advanced stages is discussed at length with a personalized, multidiscipline approach with strategies from surgical resections with various methods, to pre-, peri- and post-resection chemoradiation therapies as well as the most advanced immunotherapy. A state-of-art approach with the results of meta-analyses and large-scale randomized double-blinded clinical trials are employed throughout these chapters. For patients at the terminal ill stage, the appropriate palliative care plan is presented by experienced clinicians armed with the latest clinical practice guidelines to better manage and help those patients in the last period of their lives.
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NSAIDs and Aspirin

This volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin.

Author: Angel Lanas

Publisher: Springer

ISBN: 9783319338897

Category: Medical

Page: 263

View: 421

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This volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included. Written by experts in the field, NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists.
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Principles and Practice of Gastrointestinal Oncology

Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care.

Author: David Kelsen

Publisher: Lippincott Williams & Wilkins

ISBN: 0781776171

Category: Medical

Page: 749

View: 531

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Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care. The initial section, Principles of Gastrointestinal Oncology, includes an expanded radiation oncology chapter, an extensively revised cancer genetics chapter, and a completely rewritten medical oncology chapter emphasizing new agents. Subsequent sections focus on esophageal, gastric, pancreatic, hepatocellular, biliary tree, and colorectal cancer. Coverage of each anatomic site includes epidemiology, screening, and prevention; molecular biology and genetics; pathology; anatomy and staging; and clinical management. The final section on uncommon cancers includes new chapters on neuroendocrine tumors and small bowel cancers. A companion Website provides instant access to the complete, fully searchable text.
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Handbook of Gastrointestinal Cancers

Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care.

Author: Tanios Bekaii-Saab, MD

Publisher: Springer Publishing Company

ISBN: 9780826138132

Category: Medical

Page: 400

View: 234

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Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous gastrointestinal tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy. With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major gastrointestinal disease sites and featuring “How I Treat” case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to situations and decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource. Key Features: Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus more Includes “How I Treat” patient vignettes told from the physician’s point of view within each clinical chapter Outlines special considerations for the elderly and for survivors of gastrointestinal cancers Highlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with gastrointestinal cancers
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