Micro Drops and Digital Microfluidics

In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and ...

Author: Jean Berthier

Publisher: William Andrew

ISBN: 9781455728008

Category: Science

Page: 560

View: 894

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In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics
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Micro Drops and Digital Microfluidics

Digital. and. Droplet. Microfluidics. Compared. to. Conventional. Microflows. 1.2.1 From Microflows to Microdrops The most common—and historically first—microsystems, such as microelectrical-mechanical systems (MEMS) or lab on a chip ...

Author: Jean Berthier

Publisher: Elsevier

ISBN: 9780815518358

Category: Technology & Engineering

Page: 350

View: 398

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After spending over 12 years developing new microsystems for biotechnology – especially concerned with the microfluidic aspects of these devices – Jean Berthier is considered a leading authority in the field. Now, following the success of his book, Microfluidics for Biotechnology, Dr. Berthier returns to explain how new miniaturization techniques have dramatically expanded the area of microfluidic applications and microsystems into microdrops and digital microfluidics. Engineers interested in designing more versatile microsystems and students who seek to learn the fundamentals of microfluidics will all appreciate the wide-range of information found within Microdrops and Digital Microfluidics. The most recent developments in digital microfluidics are described in clear detail, with a specific focus on the computational, theoretical and experimental study of microdrops. • Over 500 equations and more than 400 illustrations. • Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops."" • A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates. • A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces. • Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow). • A fresh perspective on the future of microfluidics.
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Microdrops and Digital Microfluidics

In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and ...

Author: Jean Berthier

Publisher: William Andrew Pub

ISBN: 0815515448

Category: Technology & Engineering

Page: 441

View: 782

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In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. . Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops."" . A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates. . A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces. . Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow). . A fresh perspective on the future of microfluidics.
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Micro Electrode Dot Array Digital Microfluidic Biochips

Design automation and test solutions for digital microfluidic biochips. IEEE Transactions on Circuits and Systems I: Regular Papers, 57(1), 4–17. 9. Berthier, J. (2012). Micro-Drops and Digital Microfluidics. Waltham: William Andrew.

Author: Zipeng Li

Publisher: Springer

ISBN: 9783030029647

Category: Technology & Engineering

Page: 144

View: 703

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This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.
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VLSI Design and Test

Micro bubble fluidics by EWOD and ultrasonic excitation for micro bubble tweezers. In: IEEE 20th International Conference on Micro Electro Mechanical Systems MEMS 2007. IEEE (2007) 2. Berthier, J.: Micro-Drops and Digital Microfluidics.

Author: Brajesh Kumar Kaushik

Publisher: Springer

ISBN: 9789811074707

Category: Computers

Page: 815

View: 525

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This book constitutes the refereed proceedings of the 21st International Symposium on VLSI Design and Test, VDAT 2017, held in Roorkee, India, in June/July 2017. The 48 full papers presented together with 27 short papers were carefully reviewed and selected from 246 submissions. The papers were organized in topical sections named: digital design; analog/mixed signal; VLSI testing; devices and technology; VLSI architectures; emerging technologies and memory; system design; low power design and test; RF circuits; architecture and CAD; and design verification.
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Formal Modeling and Verification of Cyber Physical Systems

Fair, R. B.: Digital microfluidics: is a true lab-on-a-chip possible? Microfluidics and Nanofluidics 3, 245–281 (2007) 4. Berthier, J.: Micro-drops and digital microfluidics. William Andrew (2012) 5. Srinivasan, V., Pamula, V. K., Fair, ...

Author: Rolf Drechsler

Publisher: Springer

ISBN: 9783658099947

Category: Computers

Page: 313

View: 968

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This book presents the lecture notes of the 1st Summer School on Methods and Tools for the Design of Digital Systems, 2015, held in Bremen, Germany. The topic of the summer school was devoted to modeling and verification of cyber-physical systems. This covers several aspects of the field, including hybrid systems and model checking, as well as applications in robotics and aerospace systems. The main chapters have been written by leading scientists, who present their field of research, each providing references to introductory material as well as latest scientific advances and future research directions. This is complemented by short papers submitted by the participating PhD students.
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Microfluidics and Nanofluidics

Digital microfluidics. Annual Review of Analytical Chemistry. 2012;5:413-440. DOI: 10.1146/annurev-anchem-062011-143028 Berthier J. Micro-drops and Digital Microfluidics. 2nd ed. Netherlands: Elsevier; 2013 Madou M, Zoval J, Jia G, ...

Author: Mohsen Sheikholeslami Kandelousi

Publisher: BoD – Books on Demand

ISBN: 9781789235401

Category: Science

Page: 318

View: 822

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In the present book, various applications of microfluidics and nanofluidics are introduced. Microfluidics and nanofluidics span a broad array of disciplines including mechanical, materials, and electrical engineering, surface science, chemistry, physics and biology. Also, this book deals with transport and interactions of colloidal particles and biomolecules in microchannels, which have great importance to many microfluidic applications, such as drug delivery in life science, microchannel heat exchangers in electronic cooling, and food processing industry. Furthermore, this book focuses on a detailed description of the thermal transport behavior, challenges and implications that involve the development and use of HTFs under the influence of atomistic-scale structures and industrial applications.
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Mems Packaging

Integration method of silicon sensors on SU-8-based microfluidic platforms, Microsystem Technologies, 21(1), pp. 155–161. Berthier, J. (2012). Micro-Drops and Digital Microfluidics. William Andrew, MA, USA. Gong, J., and Kim, ...

Author: Lee Yung-cheng

Publisher: World Scientific

ISBN: 9789813229372

Category: Technology & Engineering

Page: 364

View: 236

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MEMS sensors and actuators are enabling components for smartphones, AR/VR, and wearable electronics. MEMS packaging is recognized as one of the most critical activities to design and manufacture reliable MEMS. A unique challenge to MEMS packaging is how to protect moving MEMS devices during manufacturing and operation. With the introduction of wafer level capping and encapsulation processes, this barrier is removed successfully. In addition, MEMS devices should be integrated with their electronic chips with the smallest footprint possible. As a result, 3D packaging is applied to connect the devices vertically for the most effective integration. Such 3D packaging also paves the way for further heterogenous integration of MEMS devices, electronics, and other functional devices. This book consists of chapters written by leaders developing products in a MEMS industrial setting and faculty members conducting research in an academic setting. After an introduction chapter, the practical issues are covered: through-silicon vias (TSVs), vertical interconnects, wafer level packaging, motion sensor-to-CMOS bonding, and use of printed circuit board technology to fabricate MEMS. These chapters are written by leaders developing MEMS products. Then, fundamental issues are discussed, topics including encapsulation of MEMS, heterogenous integration, microfluidics, solder bonding, localized sealing, microsprings, and reliability. Contents: Introduction to MEMS Packaging (Y C Lee, Ramesh Ramadoss and Nils Hoivik)Silex's TSV Technology: Overview of Processes and MEMS Applications (Tomas Bauer and Thorbjörn Ebefors)Vertical Interconnects for High-end MEMS (Maaike M Visser Taklo and Sigurd Moe)Using Wafer-Level Packaging to Improve Sensor Manufacturability and Cost (Paul Pickering, Collin Twanow and Dean Spicer)Nasiri Fabrication Process for Low-Cost Motion Sensors in the Consumer Market (Steven Nasiri, Ramesh Ramadoss and Sandra Winkler)PCB Based MEMS and Microfluidics (Ramesh Ramadoss, Antonio Luque and Carmen Aracil)Single Wafer Encapsulation of MEMS Resonators (Janna Rodriguez and Thomas Kenny)Heterogeneous Integration and Wafer-Level Packaging of MEMS (Masayoshi Esashi and Shuji Tanaka)Packaging of Membrane-Based Polymer Microfluidic Systems (Yu-Chuan Su)Wafer-Level Solder Bonding by Using Localized Induction Heating (Hsueh-An Yang, Chiung-Wen Lin and Weileun Fang)Localized Sealing Schemes for MEMS Packaging (Y T Cheng, Y C Su and Liwei Lin)Microsprings for High-Density Flip-Chip Packaging (Eugene M Chow and Christopher L Chua)MEMS Reliability (Chien-Ming Huang, Arvind Sai SarathiVasan, Yunhan Huang, Ravi Doraiswami, Michael Osterman and Michael Pecht) Readership: Researchers and graduate students participating in research, R&D, and manufacturing of MEMS products; professionals associated with the integration for systems represented by smartphones, AR/VR, and wearable electronics. Keywords: MEMS;Packaging;Microelectromechanical Systems;Reliability;Microstructures;Sensors;ActuatorsReview: Key Features: The book covers engineering topics critical to product development as well as research topics critical to integration for future MEMS-enabled systemsIt is a major resource for those participating in MEMS and for every professional associated with the integration for systems represented by smartphones, AR/VR and wearable electronics
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Electrowetting

Lett. 92: 244108. Pollack, M.G. (2001). Electrowetting-based microactuation of droplets for digital microfluidics. PhD Thesis, Duke University. Berthier, J. (2013). Micro-Drops and Digital Microfluidics, 2e. William Andrew, p. 560.

Author: Frieder Mugele

Publisher: John Wiley & Sons

ISBN: 9783527412402

Category: Science

Page: 350

View: 807

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Starting from the basic principles of wetting, electrowetting and fluid dynamics all the way up to those engineering aspects relevant for the development of specific devices, this is a comprehensive introduction and overview of the theoretical and practical aspects. Written by two of the most knowledgeable experts in the field, the text covers both current as well as possible future applications, providing basic working principles of lab-on-a-chip devices and such optofluidic devices as adaptive lenses and optical switches. Furthermore, novel e-paper display technology, energy harvesting and supercapacitors as well as electrowetting in the nano-world are discussed. Finally, the book contains a series of exercises and questions for use in courses on microfluidics or electrowetting. With its all-encompassing scope, this book will equally serve the growing community of students and academic and industrial researchers as both an introduction and a standard reference.
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Green Analytical Chemistry

The As one use Droplet/digital of can droplet see, the microfluidics considerable microfluidics now advantage ... that of microfluidics microflow systems, have in hence, common adherence the use and of microdrops adhesion problems and ...

Author: Mihkel Koel

Publisher: Royal Society of Chemistry

ISBN: 9781782626008

Category: Science

Page: 332

View: 277

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Concerns about environmental pollution, global climate change and hazards to human health have increased dramatically. This has led to a call for change in chemical processes including those that are part of chemical analysis. The development of analytical chemistry continues and every new discovery in chemistry, physics, molecular biology, and materials science brings new opportunities and challenges. Yet, contemporary analytical chemistry does not consume resources optimally. Indeed, the usage of toxic chemical compounds is at the highest rate ever. All this makes the emerging field of green chemistry a “hot topic” in industrial, governmental laboratories as well as in academia. This book starts by introducing the twelve principles of green chemistry. It then goes on to discuss how the principles of green chemistry can be used to assess the ‘greenness’ of analytical methodologies. The ‘green profile’ proposed by the ACS Green Chemistry Institute is also presented. A chapter on “Greening” sample preparation describes approaches to minimizing toxic solvent use, using non-toxic alternatives, and saving energy. The chapter on instrumental methods describes existing analytical approaches that are inherently green and making non-green methods greener. The final chapter on signal acquisition describes how quantitative structure-property relationship (QSPR) ideas could reduce experimental work thus making analysis greener. The book concludes with a discussion of how green chemistry is both possible and necessary. Green Analytical Chemistry is aimed at managers of analytical laboratories but will also interest teachers of analytical chemistry and green public policy makers.
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