Radiotherapy of Liver Cancer

This book provides up-to-date information on all aspects of radiotherapy for liver cancer, from the basic science to clinical practice.

Author: Jinsil Seong

Publisher: Springer Nature

ISBN: 9789811618154

Category: Medical

Page: 337

View: 416

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This book provides up-to-date information on all aspects of radiotherapy for liver cancer, from the basic science to clinical practice. While demand for radiotherapy of liver cancer has been increasing, the guidance available to clinicians has remained limited. Radiotherapy of Liver Cancer aims to address this deficit on the basis of the best available evidence. The first two sections explain the relevant basic science and present detailed information on the available technologies and techniques, including the most recent advances. The radiotherapy strategies appropriate in different patient groups are then fully described, covering the use of ablative, adjuvant, neoadjuvant, and definitive radiotherapy, radiotherapy as a bridge to liver transplantation, and palliative radiotherapy. The final section addresses a range of specific issues of concern to the clinician. Radiotherapy of Liver Cancer will be an ideal reference for clinical radiation oncologists, radiation oncology residents, oncologists, and hepatologists.
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Radiation Therapy for Liver Tumors

This book examines basic principles of the management of liver tumors. The evolving roles of x-ray and particle therapies as well as radioembolization in the treatment of liver tumors is the main focus.

Author: Jeffrey Meyer

Publisher: Springer

ISBN: 9783319545318

Category: Medical

Page: 288

View: 228

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The management of liver tumors is a nexus of interactions among multiple medical specialties, including radiation oncology. A multitude of liver-directed therapies are available for patients, ranging from surgery and liver transplantation to intra-arterial therapies, thermal ablation procedures, systemic therapies, and radiation treatments. With the introduction of hypofractionated irradiation, particle therapy, and radioembolization, there is growing interest in the use of radiation as a treatment for liver malignancies. This book examines basic principles of the management of liver tumors. The evolving roles of x-ray and particle therapies as well as radioembolization in the treatment of liver tumors is the main focus. A theme of multidisciplinary management is also emphasized, as surgical, interventional and systemic therapies are reviewed. A unique resource that discusses the role of radiation treatment in the context of other liver-directed therapies, Radiation Therapy for Liver Tumors is of broad interest to radiation oncologists, surgeons, hepatologists, medical oncologists, and radiologists.
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Liver Cancer

The purpose of this book is to collect in one volume an integrated selection of articles that would provide the therapist with a comprehensive, yet practical, overview of liver cancer.

Author: Joseph C. Bottino

Publisher: Springer Science & Business Media

ISBN: 9781461325932

Category: Medical

Page: 392

View: 439

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Neoplastic disease confined to the liver is an important worldwide problem. In the industrialized nations, metastatic disease of the most common cancers involves the liver in upwards of 50% of cases. Primary hepatic tumors are virtually epidemic in most third world countries and certainly constitute one of the ten most common causes of cancer deaths on a worldwide scale. Amazingly, little specific attention has been devoted to therapeutic approaches of liver and biliary tumors until recently. We attribute this apparent lack of interest to the uniformly poor progno sis of patients so afflicted, and attribute the renewed interest to the exciting new developments in diagnostic and therapeutic technology as well as in tumor biology. The purpose of this book is to collect in one volume an integrated selection of articles that would provide the therapist with a comprehensive, yet practical, overview of liver cancer. We believe the contributors to the book are superbly qualified experts on the various subjects and provide in-depth information on respective fields. The edit ing process for us was not only educational but thrilling as the high quality and complementary nature of the chapters became evident as we received them. Be cause many areas in the field of liver cancer are controversial, the reader will notice that contradictory opinions are presented by some of the authors.
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Biliary Tract and Primary Liver Tumors An Issue of Surgical Oncology Clinics of North America

Expert authors in this issue review this topic in articles such as: Epidemiology and Risk Factors of Biliary Tract Tumors and Primary Liver Tumors; Imaging of the Patient with a Biliary Tract or Primary Liver Tumor; Percutaneous and ...

Author: Timothy M Pawlik

Publisher: Elsevier Health Sciences

ISBN: 9780323290197

Category: Medical

Page: 257

View: 452

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This issue of Surgical Oncology Clinics of North America is devoted to "Biliary Tract and Primary Liver Tumors" and is edited by Timothy Pawlik, MD, of the Johns Hopkins Hospital in Baltimore. Expert authors in this issue review this topic in articles such as: Epidemiology and Risk Factors of Biliary Tract Tumors and Primary Liver Tumors; Imaging of the Patient with a Biliary Tract or Primary Liver Tumor; Percutaneous and Endoscopic Approaches to Biliary Tract Tumors and Primary Liver Tumors; Intrahepatic Cholangiocarcinoma; Hilar Cholangiocarcinoma; Distal Cholangiocarcinoma; Hepatocellular Carcinoma; Staging of Biliary Tract and Primary Liver Tumors; Intra-arterial Therapies: Primary Liver Tumors; Radiotherapy: Primary Liver Tumors; Systemic and Targeted Therapy; and Palliation: Treating Patients with Inoperable Biliary Tract and Primary Liver Tumors.
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Trends and Practices in Diagnosis and Treatment of Hepatocellular Carcinoma

This publication has been written for students and professionals in radiation oncology and cancer control programmes. It serves as a source of information on treatment decisions with regard to hepatocelluar carcinoma (HCC) or liver cancer.

Author: International Atomic Energy Agency

Publisher:

ISBN: 9201027109

Category: Technology & Engineering

Page: 89

View: 248

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This publication has been written for students and professionals in radiation oncology and cancer control programmes. It serves as a source of information on treatment decisions with regard to hepatocelluar carcinoma (HCC) or liver cancer. Radiotherapy plays a major role in the treatment of HCC, which is one of the most common causes of cancer death globally. However, to date there were no uniform recommendations, and the use of radiotherapy is limited by pre-existing liver disease. The present publication reports the results of an assessment of the role of radiotherapy within the entire framework of HCC management. It may guide the appropriate use of limited resources towards the most appropriate indications, and help in differentiating approaches used for cure or palliation of HCC.
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Hepatocellular Carcinoma

This volume also provides an up-to-date guide for treatment that explores not only traditional treatments, but newer investigational treatment options including, surgical resection, liver transplantation, ablation (radiofrequency, ...

Author: Kelly M. McMasters

Publisher: Springer Science & Business Media

ISBN: 9781603275224

Category: Medical

Page: 415

View: 985

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Hepatocellular Carcinoma: Targeted Therapy provides a detailed repository of the latest information regarding HCC epidemiology, diagnosis, imaging, pathology, staging, and treatment options. This volume also provides an up-to-date guide for treatment that explores not only traditional treatments, but newer investigational treatment options including, surgical resection, liver transplantation, ablation (radiofrequency, microwave), percutaneous ethanol or acetic acid injection, transarterial chemoembolization (TACE), intra-arterial radiation therapy, and systemic chemotherapy. Heptocellular Carcinoma: Targeted Therapy will be of great value to all health care professionals and trainees worldwide who have an interest in the diagnosis and treatment of HCC, including surgeons, medical oncologists, radiologists, radiation oncologists, and pathologists.
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Liver Cancer

Liver Cancer provides the general surgeon, surgical oncologist, and medical oncologist with the most current standard of multimodality care for hepatobiliary cancer.

Author: Steven A. Curley

Publisher: Springer Science & Business Media

ISBN: 0387983708

Category: Medical

Page: 274

View: 505

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Liver Cancer provides the general surgeon, surgical oncologist, and medical oncologist with the most current standard of multimodality care for hepatobiliary cancer. Surgical approaches, chemotherapy, immunotherapy, gene therapy, and radiotherapy are all presented.
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Liver Radioembolization with 90Y Microspheres

This vital text for oncologists and radiotherapists provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors.

Author: José Ignacio Bilbao

Publisher: Springer Science & Business Media

ISBN: 9783540354239

Category: Medical

Page: 164

View: 951

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This vital text for oncologists and radiotherapists provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. Radioembolization combines embolization (intravascular deployment of particles – microspheres loaded with yttrium-90) and brachytherapy (local administration of radiotherapy), thereby allowing delivery of high doses of beta-radiation specifically to the tumoral area.
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Modeling of the Liver Deformation During Breathing in Radiation Therapy

In this work, thirty patients were studied. First, we created a model for every individual patient by comparing the deformation in the end-exhale position image to that in the inhale position image. Thirty models were created.

Author:

Publisher:

ISBN: OCLC:1005352014

Category: Image registration

Page: 67

View: 886

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"Radiation treatment of liver cancer is challenging because the liver and the neighboring organs such as the stomach, small bowel, and esophagus should receive a minimum dose. The localization of the tumor at the treatment session is an important stage to define the dose for the tumor and for the neighboring normal tissue. The localization of liver tumor is very challenging because of the changes to the liver anatomy due to stomach filing, patient positioning, and breathing motion. During breathing, the shape of the liver changes. This change can vary from one person to another and can even vary from day to day for the same person. Image registration can be used to connect treatment images with planning images to define the changes during breathing motion for tumor localization. In this work, thirty patients were studied. First, we created a model for every individual patient by comparing the deformation in the end-exhale position image to that in the inhale position image. Thirty models were created. The displacement field map was calculated for each model, and it was found that the maximum displacement is toward the superior/inferior direction. After that, preprocessing steps for each patient were conducted to create the mean population model. The first step was drawing a manual contour for each end-exhale phase for each patient. Then, one patient was chosen to be the reference patient. After that, the MORFEUS algorithm was performed to align every patient to the reference patient. We did apply linear interpolation to put all patients in the same orientation. We also found the average displacement for the population to create a final global model of the liver. This result will help to improve the treatment of liver cancer"--from abstract.
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