Taurine 9

Taurine is an abundant amino acid that is essential for the cat but semi-essential for man (Knopf et al. 1978; Gaull 1986). Taurine is synthesized from cysteine in the liver. While the biosynthesis of taurine is depressed or absent in ...

Author: Janusz Marcinkiewicz

Publisher: Springer

ISBN: 9783319151267

Category: Science

Page: 905

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Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May 2014. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
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Taurine 2

Biochemical markers for compounds which affect GSH levels Urinary Serum Serum Total Serum Taurine 9% Serum Serum Total Bilirubin Albumin Treatment Lesion Change ALT iu/L AST iu/L Protein g/L umol/L g/L Diethyl maleate Depletes J-69**(2) ...

Author: Ryan J. Huxtable

Publisher: Springer Science & Business Media

ISBN: 9781489901828

Category: Science

Page: 658

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This volume comprises the edited proceedings of the International Taurine Sympo sium held in Osaka, Japan, in June 1995, as a Satellite Symposium of the 15th Biennial of the International Society for Neurochemistry. This Taurine Symposium was the Meeting latest in a series held since 1975 at approximately two-year intervals by an informal group of international researchers. It attracted contributions from 20 countries, ranging from Armenia via Finland and Spain to the United States. Some 121 participants attended. The Symposium was organized and chaired by Junichi Azuma, University of Osaka. Other members of the Organizing Committee in Japan consisted of Kinya Kuriyama and Masao Nakagawa, both from the Kyoto Prefectural University of Medicine, and Akemichi Baba, from Osaka University. The Committee had to contend with the disaster of the Kobe earthquake, which struck on January 21. The epicenter was only around 25 miles from the meeting site, and the quake demolished the home of one Committee member. Despite this unnaturally natural handicap, the participants experienced a superbly organized meeting, one which more than maintained the high social and scientific standards established for this series. In his Welcome Message, Dr. Azuma listed a threefold objective for the Symposium: To provide a forum for the interdisciplinary exchange of information on taurine; to give an opportunity for renewing old friendships and making new friends; and to promote coopera tion among participants from around the world.
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Taurine 10

3 Results 3.1 Effects of Taurine on the Survival of PC12 Cells Exposed to HBCD Exposure to 10 μM HBCD for 24 h, the cell death rate was 66.23 ± 4.13% comparing with the control group. Pretreatment with 1, 3 and 9 mMtaurine significantly ...

Author: Dong-Hee Lee

Publisher: Springer

ISBN: 9789402410792

Category: Science

Page: 1212

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Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
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The Biology of Taurine

Cysteine dioxygenase of rat liver is induced by the injection of hydrocortisone or sulfur amino acids such as cysteine or methionine and is highly responsive to the dietary intake of sulfur amino acids (2,9,16,21) and protein (9), ...

Author: Ryan J. Huxtable

Publisher: Springer Science & Business Media

ISBN: 9781489904058

Category: Medical

Page: 406

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I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The book is the outcome of the Symposium held in Firenze-San Miniato (PI), October 6-9, 1986. The symposium was entitled "Sulfur Amino Acids, Peptides and Related Compounds" and was the 7th international symposium on taurine ßnd assooiated substances. It is always difficult to introduce, with the right brevity end emphasis, a topic which has been studied in depth by numerous experte. Nevertheless, I shall do my best to give a historical perspeotive of the subjects of the meeting which I consider to be very important for the frontiers of researoh on taurine. ~he following topios have also beoome coherent areas of study during the development of researoh on taurine: metabolism, nutrition, neurochemistry, cardiovasoular regulation. Although taurine was isolated in 1821 by ~iedman and Gmel1n, its only biochemioal role known at the time was the synthesis of bile saIte in mammalian tissue. There has been an inoreasing interest in the biologioal action of taurine from metabolio aspects to other biologioal aspects (nutrition, development, eto.). In 1975 it was first demonstrated that taurine deprivation produoed retinal degeneration in cats; more reoent studies showed that a taurine-free diet or the administration of taurine transport inhibitors caused retinal degeneration in other mammlas. More reoent studies have pointed out the role of taurine in development, and the first part of this book is dedicated to these topios.
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Taurine and the Heart

Embryonic (20 day old) Chick Hearts Contractions Accompanying Slow APs I- + Taurine (10mM) — + Histamine Control 25 mMK* - * Verapamil (10"M) 1-2 min 7 min (2x10"M) C F. | 10 or 50 W. We 40 mV. |* 200 ms F Figure 1–9.

Author: Heitaroh Iwata

Publisher: Springer Science & Business Media

ISBN: 9781461316473

Category: Medical

Page: 164

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The first Taurine Symposium organized by Dr. Ryan Huxtable and the late Dr. Andre Barbeau was held in Tucson, Arizona, in 1975. Since that auspici ous event, nine international symposia on the role of taurine in biology have taken place. The locations for these meetings have been Tucson (two times), Rome, Philadelphia, Tokyo, Vancouver, Mexico City, Helsinki, and Florence. In 1977, due to the large number of scientists in Japan who were interested in the role of this unique amino acid in biological systems, we organized the Japanese Research Society on Sulfur Amino Acids with the encouragement and financial assistance of the Taisho Pharmaceutical Co., Ltd (Tokyo). Annual meetings have been held, and the membership has expanded from 78 to 414 in 1987; the number of presentations has increased during this time span from 29 to 74. The symposium in Tokyo in 1982, "Sulfur Amino Acids, Biochemical and Clinical Aspects" [1], was held to celebrate the 5th Annual Meeting of our Society. I would like to emphasize that in Japan we have an active Research Society especially directed to the study of sulfur amino acids. We have published our own semi-annual journal entitled Sulfur Amino Acids. Our society is an inter disciplinary research society since taurine is a highly diversified compound that interconnects physiology, biochemistry, pharmacology, nutrition, and medicine. One exciting fringe benefit of taurine research and the society has been the fostering of contacts with distinguished scientists from many varied medical fields.
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Taurine 8

control levels, whereas, interestingly, the concentration of taurine was significantly increased when measured 24 h ... Taurine (100 mg/kg) or equal volume of saline was administered IP for 9 days to rats before subjecting them to ...

Author: Abdeslem El Idrissi

Publisher: Springer Science & Business Media

ISBN: 9781461461302

Category: Science

Page: 454

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Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in the Nervous System, Taurine in the Immune System, Taurine and Diabetes, and Taurine and the Cardiovascular System. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L’Amoreaux, College of Staten Island, were co-chairs of the Organizing Committee for the meeting. Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.
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Class 2 Transferases III

Natural substrates and products S choloyl-CoA + glycine <1, 2> (<1,2> taurine can replace glycine, involved in conjugation of bile acids [2,4,9]; <1> conjugation of bile acids in the liver with glycine or taurine prior to being secreted ...

Author: Antje Chang

Publisher: Springer Science & Business Media

ISBN: 9783540377177

Category: Science

Page: 698

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The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
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School Archives

9 + 1 . 3 5 . 5 + 2 . 8 urinary loss of the administered taurine was Beef 30 . 2 + 17 . 5 12 . 1 + 2 . 7 6 . 37 + 0 . 8 less in the psoriatic subjects than in the conCod 38 . 0 + 4 . 3 32 . 8 + 6 . 8 16 . 1 + 3 .

Author:

Publisher:

ISBN: CORNELL:31924074253463

Category: Nutrition

Page:

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Taurine 4

Dulbecco's modified medium (DMEM) and [2-'H(N)]-Taurine (21.9 Ci/mmol) were rom Gibco-BRL (Grand Island, NY) and NEN (Boston, MA), ely. Fetal bovine serum (FBS), penicillin and streptomycin, masone (Dex), PMA, taurine, 9-alanine, ...

Author: Laura Della Corte

Publisher: Springer Science & Business Media

ISBN: 9780306468384

Category: Science

Page: 652

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Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3μM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .
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Taurine in Health and Disease

Hence, hypotaurine is typically found in sperm, neutrophils, liver and neural tissues, including retinal tissue subjected to photolytic oxidative stress, all of which likewise contain very high levels of taurine (9).

Author: Ryan J. Huxtable

Publisher: Springer Science & Business Media

ISBN: 9781489914712

Category: Science

Page: 458

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Taurine, or 2-aminoethane sulfonic acid, has long been known to be the major organic product formed from the breakdown of the sulfur-containing amino acids, methionine and cysteine. It is excreted as such in the urine or as bile acid conjugates in the bile. Research over the last 25 years, however, has uncovered an amazing variety of phenomena involving taurine. Despite the fact that the mechanism of action of taurine in some of these phenomena remains to be elucidated, it is clear that taurine is of far more physiological relevance than being the mere metabolic debris of sulfur amino acid catabolism. It also has numerous pharmacological actions that are beginning to be developed, as exemplified by some of the studies reported in this volume. This volume reports the proceedings of the latest of a series of international symposia, continuing on from the initial meeting held in Tucson, Arizona, in 1975. The latest symposium was the first to be held in Germany, in Cologne from August 29 through September 1, 1993. It continued the multidisciplinary approach that has been the norm for taurine symposia. We hope the publication of the proceedings will stimulate further investigations on this simple but fascinating compound.
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