The Genome Factor

These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more ...

Author: Dalton Conley

Publisher:

ISBN: 0691164746

Category: Science

Page: 304

View: 344

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For a century, social scientists have avoided genetics like the plague. But in the past decade, a small but intrepid group of economists, political scientists, and sociologists have harnessed the genomics revolution to paint a more complete picture of human social life than ever before. "The Genome Factor" describes the latest astonishing discoveries being made at the scientific frontier where genomics and the social sciences intersect. "The Genome Factor" reveals that there are real genetic differences by racial ancestry--but ones that don't conform to what we call black, white, or Latino. Genes explain a significant share of who gets ahead in society and who does not, but instead of giving rise to a genotocracy, genes often act as engines of mobility that counter social disadvantage. An increasing number of us are marrying partners with similar education levels as ourselves, but genetically speaking, humans are mixing it up more than ever before with respect to mating and reproduction. These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more of us are taking advantage of cheap genotyping services like 23andMe to find out what our genes may hold in store for ourselves and our children. "The Genome Factor" shows how genomics is transforming the social sciences--and how social scientists are integrating both nature and nurture into a unified, comprehensive understanding of human behavior at both the individual and society-wide levels.
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The Genome Factor

What the Social Genomics Revolution Reveals about Ourselves, Our History, and
the Future Dalton Conley, Jason Fletcher. THE GENOME FACTOR THE
GENOME FACTOR What the Social Genomics Revolution Reveals about Front
Cover.

Author: Dalton Conley

Publisher: Princeton University Press

ISBN: 9780691183169

Category: Science

Page: 296

View: 298

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For a century, social scientists have avoided genetics like the plague. But in the past decade, a small but intrepid group of economists, political scientists, and sociologists have harnessed the genomics revolution to paint a more complete picture of human social life than ever before. The Genome Factor describes the latest astonishing discoveries being made at the scientific frontier where genomics and the social sciences intersect. The Genome Factor reveals that there are real genetic differences by racial ancestry--but ones that don't conform to what we call black, white, or Latino. Genes explain a significant share of who gets ahead in society and who does not, but instead of giving rise to a genotocracy, genes often act as engines of mobility that counter social disadvantage. An increasing number of us are marrying partners with similar education levels as ourselves, but genetically speaking, humans are mixing it up more than ever before with respect to mating and reproduction. These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more of us are taking advantage of cheap genotyping services like 23 and Me to find out what our genes may hold in store for ourselves and our children. The Genome Factor shows how genomics is transforming the social sciences--and how social scientists are integrating both nature and nurture into a unified, comprehensive understanding of human behavior at both the individual and society-wide levels. --
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Chromosomes Today

Since S also differs from the P genome by V chromosome rearrangements , it
could be that the bivalent pairing in the SSP triploid was due to the same S
genome factor . It is also possible that a similar factor exists in the P genome ,
hence the ...

Author: P. L. Pearson

Publisher: John Wiley & Sons

ISBN: UIUC:30112009289429

Category: Chromosomes

Page: 473

View: 921

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Nature Encyclopedia of the Human Genome

Factor V ( FV ) Leiden is the most common genetic risk factor for venous
thrombosis . It is caused by a single point mutation in the factor V gene ( F5 ) ,
which results in the replacement of arginine at position 506 with a glutamine .
Arginine 506 ...

Author: David N. Cooper

Publisher: Natures Pub Limited

ISBN: UOM:39015056925863

Category: Human genetics

Page: 1135

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Nature Encyclopedia of the Human Genome is the only reference resource devoted entirely to the scientific basis and genetics and genomics research and the complex commercial, philosophical, and ethical questions that arise from it. It presents a comprehensive and rigorously detailed overview of current genome science and its groundbreaking applications, examining the many topics that surround the field from the differing perspectives of history, philosophy, ethics, law, medicine, public health, and industry. Core areas covered include: structural genomics, functional genomics, chromosome structure and function, evolution and comparative genomics, genome mapping and sequencing, genes and disease, behavioural and psychiatric genetics, mathematical and population genetics, proteomics, bioinformatics, ethical, legal and social issues and biographies or key figures.
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Genome Research

For example , the promoter of the hepatocyte growth 74 % of Ensembl genes (
July 2003 freeze of UCSC Genome factor ( MET ) gene was active in only seven
of the 16 cell lines and Browser ) ( Karolchik et al . 2003 ) . Consistent with our ...

Author:

Publisher:

ISBN: NWU:35558005516154

Category:

Page:

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Aging of the Genome

This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology.

Author: Jan Vijg

Publisher: Oxford University Press

ISBN: 9780198569220

Category: Medical

Page: 372

View: 559

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Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology.
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Cell Structure and Function

( 2 ) Genome factor . The genome are inheritable factors which reside in the
chromosome and segregates in Mendelian fashion ; when mutations occur the
phenotypic expression of the plastids may be altered . According to Demerec (
1935 ) ...

Author: A. T. Varute

Publisher: International Book Distributors

ISBN: UIUC:30112009874774

Category: Cell physiology

Page: 343

View: 445

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A Handbook of Transcription Factors

This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying ...

Author: Timothy R. Hughes

Publisher: Springer Science & Business Media

ISBN: 904819069X

Category: Medical

Page: 306

View: 857

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Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
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Social by Nature

This book is a powerful call for researchers to approach their work in more socially responsible ways, and a must-read for anyone who wants to better understand the scholarship that impacts how we see ourselves and our society.

Author: Catherine Bliss

Publisher: Stanford University Press

ISBN: 9781503603967

Category: Social Science

Page: 304

View: 606

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Sociogenomics has rapidly become one of the trendiest sciences of the new millennium. Practitioners view human nature and life outcomes as the result of genetic and social factors. In Social by Nature, Catherine Bliss recognizes the promise of this interdisciplinary young science, but also questions its implications for the future. As she points out, the claim that genetic similarities cause groups of people to behave in similar ways is not new—and a dark history of eugenics warns us of its dangers. Over the last decade, sociogenomics has enjoyed a largely uncritical rise to prominence and acceptance in popular culture. Researchers have published studies showing that things like educational attainment, gang membership, and life satisfaction are encoded in our DNA long before we say our first word. Strangely, unlike the racial debates over IQ scores in the '70s and '90s, sociogenomics has not received any major backlash. By exposing the shocking parallels between sociogenomics and older, long-discredited, sciences, Bliss persuasively argues for a more thoughtful public reception of any study that reduces human nature to a mere sequence of genes. This book is a powerful call for researchers to approach their work in more socially responsible ways, and a must-read for anyone who wants to better understand the scholarship that impacts how we see ourselves and our society.
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Advances in Forest Genetics

The larger the genome size , the more dilute the concentration of individual
sequences becomes , and the slower the reannealing reaction will proceed . The
second genome factor that affects reannealing rate is the presence of repetitious
 ...

Author: P. K. Khosla

Publisher:

ISBN: CORNELL:31924086710112

Category: Forest genetics

Page: 375

View: 339

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Contributed articles.
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Molecular Biology

When sequences of the factor IX gene were compared in different species it
appeared that the " hottest " CG sites in ... The process of accumulation of CGTG
+ CA transitions in the human genome is rather active ; it influences not only the ...

Author:

Publisher:

ISBN: STANFORD:36105016979119

Category:

Page:

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The Ends of the Genome of Bacteriophage Mu

In all experiments described the transposition was induced at 38 ° C and not at
42 ° C . Induction for 1 hr at 42 ° C resulted in a decrease of the transfer of the F
pro * lac + episome by a factor of 200. This interference with F transfer was not ...

Author: Martinus A. Groenen

Publisher:

ISBN: CORNELL:31924059885362

Category:

Page: 108

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Transcription Factor Binding Site Modeling in Higher Organisms

Repetitive Elements A distinguishing feature of higher organisms , particularly
human , is the large amount of repetitive sequence embedded in the genome .
Repetitive elements are sequences that repeat themselves identically or almost ...

Author: Lawrence Sean Hon

Publisher:

ISBN: UCAL:X85522

Category:

Page: 248

View: 640

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It is hoped that these efforts using large-scale datasets and efficient algorithms will allow further advances in understanding mammalian transcriptional regulation at the sequence level.
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Mechanisms of Gene Regulation

The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters.

Author: Carsten Carlberg

Publisher: Springer

ISBN: 9789401777414

Category: Medical

Page: 211

View: 355

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This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule stating that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.
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The Human Genome Project

whatever eye color factor might be on the X chromosome ? If so , then the eggs of
XX females , which could only produce X - containing gametes , would have to be
fertilized by a Y chromosome in order to produce a male . If the X chromosome ...

Author: Thomas F. Lee

Publisher: Springer

ISBN: 0306439654

Category: Medical

Page: 323

View: 285

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Provides a history of the project, and discusses its implications, ethics, potential products, and the people involved
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Cambridge Scientific Biochemistry Abstracts

Late RNA present in infected cells after DNA replication hybridized with
essentially all the genome . The RNA ... binding factors are required at the
establishment but not the maintenance step of enhancer - dependent
transcriptional activation .

Author:

Publisher:

ISBN: UCAL:B3873726

Category: Biochemistry

Page:

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Genomic Imprinting

Thus , the model does not consider complex interactions among factors . The
qualitative conclusions of this model should also apply in more complex models .
Genomic factions Consider a set of agents ( present in the genome of an off ...

Author: Hiroyuki Sasaki

Publisher: S Karger Ag

ISBN: WISC:89090429895

Category: Medical

Page: 349

View: 726

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Genomic imprinting, a parent-of-origin-specific epigenetic modification of the genome, is observed in placental mammals and some plants (angiosperms). Since its discovery in the early 1980s, this intriguing phenomenon has been intensively investigated and has spawned an exciting new research area. Imprinting is relevant to a variety of biological events such as embryogenesis, growth and behavior, and its disruption can lead to congenital malformation syndromes and cancers. Furthermore, imprinting has been serving as an excellent model system to study epigenetic mechanisms of gene regulation and helping us to understand how gene clusters and genome domains are regulated. This special issue provides an overview of the current knowledge of genomic imprinting. Including both excellent reviews and original research articles by outstanding researchers in the field, many of which were participants of the genomic imprinting workshops in Montpellier (September 2004) and Oxford (April 2005), it represents the forefront of imprinting research.
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Biometrics

There appears to be no name in the genetic literature for factors such as Xisi and
Xes2 , functions of which comprise the genotypes . Following a suggestion given
by R. L. Willham , we call the variables Xesi and X182 the genomic values of ...

Author:

Publisher:

ISBN: UCAL:B5031644

Category: Biometry

Page:

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Junk DNA

Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists.

Author: Nessa Carey

Publisher: Icon Books

ISBN: 9781848318267

Category: Science

Page: 288

View: 905

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From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.
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Studies on the Bacteriophage SPO1 Transcription Factor 1

The genome of SPOI Is a doublestranded DNA molecule that is 145 kbp in length
( Parker and Eiserling , 1983b ; Lawrie et al , 1978 ; Pero et al , 1979 ) . There are
two unusual structural features of this DNA : 1 ) The SPOI genome contains ...

Author: Jonathan Richard Greene

Publisher:

ISBN: UCSD:31822003768454

Category:

Page: 322

View: 936

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